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Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men

3 Apr 2015

Abstract excerpt

Increasing evidence suggests that aberrant DNA methylation changes may contribute to prostate cancer (PCa) ethnic disparity. To comprehensively identify DNA methylation alterations in PCa disparity, we used the Illumina 450K methylation platform to interrogate the methylation status of 485,577 CpG sites focusing on gene-associated regions of the human genome. Genomic DNA from African-American (AA; 7 normal and 3...

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PMID: 25864488
DOI: 10.1080/15592294.2015.1022019

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