Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Glycosylation Mutant of Trypanosoma brucei Links Social Motility Defects In Vitro to Impaired Colonization of Tsetse Flies In Vivo.

Eukaryotic cell - 1 Jun 2015

Imhof Simon, Vu Xuan Lan, Bütikofer Peter, Roditi Isabel

Abstract excerpt

Transmission of African trypanosomes by tsetse flies requires that the parasites migrate out of the midgut lumen and colonize the ectoperitrophic space. Early procyclic culture forms correspond to trypanosomes in the lumen; on agarose plates they exhibit social motility, migrating en masse as radial projections from an inoculation site. We show that an Rft1(-/-) mutant needs to reach a greater threshold number...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to Protozoan Proteins
Share to Trypanosoma brucei brucei

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Tsetse Flies

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 25862152
DOI: 10.1128/EC.00023-15
PMCID: PMC4452570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Glycosylation Mutant of Trypanosoma brucei Links Social Motility Defects In Vitro to Impaired Colonization of Tsetse Flies In Vivo.PMID 25862152Read ↗

Persistence of Trypanosoma brucei as early procyclic forms and social motility are dependent on glycosylphosphatidylinositol transamidase.Semantic proximity Read ↗

Flagellar cAMP signaling controls trypanosome progression through host tissuesSemantic proximity Read ↗

Trypanosome Infection Establishment in the Tsetse Fly Gut Is Influenced by Microbiome-Regulated Host Immune BarriersSemantic proximity Read ↗

Social Motility in African TrypanosomesSemantic proximity Read ↗

Parasite motility is critical for virulence of African trypanosomes.Semantic proximity Read ↗

Developmental Progression to Infectivity in <i>Trypanosoma brucei</i> Triggered by an RNA-Binding ProteinSemantic proximity Read ↗

Insect Stage-Specific Adenylate Cyclases Regulate Social Motility in African TrypanosomesSemantic proximity Read ↗

Glycosylation of <i>Plasmodium falciparum</i> TRAP supports sporozoite motility and invasionSemantic proximity Read ↗

Forward motility is essential for trypanosome infection in the tsetse flySemantic proximity Read ↗

Tsetse peritrophic matrix influences for trypanosome transmissionSemantic proximity Read ↗

Glycoprotein biosynthesis in a eukaryote lacking the membrane protein Rft1.Semantic proximity Read ↗

Infections with Immunogenic Trypanosomes Reduce Tsetse Reproductive Fitness: Potential Impact of Different Parasite Strains on Vector Population StructureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.