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Article

Parasite motility is critical for virulence of African trypanosomes.

Scientific reports - 14 Jun 2018

Shimogawa Michelle M, Ray Sunayan S, Kisalu Neville, Zhang Yibo, Geng Quanjie, Ozcan Aydogan, Hill Kent L

Abstract excerpt

African trypanosomes, Trypanosoma brucei spp., are lethal pathogens that cause substantial human suffering and limit economic development in some of the world's most impoverished regions. The name Trypanosoma ("auger cell") derives from the parasite's distinctive motility, which is driven by a single flagellum. However, despite decades of study, a requirement for trypanosome motility in mammalian host infection...

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Identifiers

PMID: 29904094
DOI: 10.1038/s41598-018-27228-0
PMCID: PMC6002391

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