Article
Extensive Capsule Locus Variation and Large-Scale Genomic Recombination within the Klebsiella pneumoniae Clonal Group 258.
Genome biology and evolution - 10 Apr 2015
Wyres Kelly L, Gorrie Claire, Edwards David J, Wertheim Heiman F L, Hsu Li Yang, Van Kinh Nguyen, Zadoks Ruth, Baker Stephen, Holt Kathryn E
Abstract excerpt
Klebsiella pneumoniae clonal group (CG) 258, comprising sequence types (STs) 258, 11, and closely related variants, is associated with dissemination of the K. pneumoniae carbapenemase (KPC). Hospital outbreaks of KPC CG258 infections have been observed globally and are very difficult to treat. As a consequence, there is renewed interest in alternative infection control measures such as vaccines and phage or...
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