Article
Population structure of KPC-producing Klebsiella pneumoniae isolates from midwestern U.S. hospitals.
Antimicrobial agents and chemotherapy - 1 Aug 2014
Wright Meredith S, Perez Federico, Brinkac Lauren, Jacobs Michael R, Kaye Keith, Cober Eric, van Duin David, Marshall Steven H, Hujer Andrea M, Rudin Susan D, Hujer Kristine M, Bonomo Robert A, Adams Mark D
Abstract excerpt
Genome sequencing of carbapenem-resistant Klebsiella pneumoniae isolates from regional U.S. hospitals was used to characterize strain diversity and the bla(KPC) genetic context. A phylogeny based on core single-nucleotide variants (SNVs) supports a division of sequence type 258 (ST258) into two distinct groups. The primary differences between the groups are in the capsular polysaccharide locus (cps) and their...
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