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Article

Pore forming activity of the potent RTX-toxin produced by pediatric pathogen Kingella kingae: Characterization and comparison to other RTX-family members.

Biochimica et biophysica acta - 1 Jul 2015

Bárcena-Uribarri Iván, Benz Roland, Winterhalter Mathias, Zakharian Eleonora, Balashova Nataliya

Abstract excerpt

Pediatric septic arthritis in patients under age of four is frequently caused by the oral Gram-negative bacterium Kingella kingae. This organism may be responsible for a severe form of infective endocarditis in otherwise healthy children and adults. A major virulence factor of K. kingae is RtxA, a toxin that belongs to the RTX (Repeats-in-ToXin) group of secreted pore forming toxins. To understand the RtxA...

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Identifiers

PMID: 25858109
DOI: 10.1016/j.bbamem.2015.03.036
PMCID: PMC4430422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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