Set-based tests for genetic association in longitudinal studies.

doi:10.1111/biom.12310

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Set-based tests for genetic association in longitudinal studies.

Biometrics - 1 Sept 2015

He Zihuai, Zhang Min, Lee Seunggeun, Smith Jennifer A, Guo Xiuqing, Palmas Walter, Kardia Sharon L R, Diez Roux Ana V, Mukherjee Bhramar

Abstract excerpt

Genetic association studies with longitudinal markers of chronic diseases (e.g., blood pressure, body mass index) provide a valuable opportunity to explore how genetic variants affect traits over time by utilizing the full trajectory of longitudinal outcomes. Since these traits are likely influenced by the joint effect of multiple variants in a gene, a joint analysis of these variants considering linkage...

Topics

Atherosclerosis
Computer Simulation
Data Interpretation, Statistical
Genetic Association Studies
Genetic Markers
Genetic Predisposition to Disease
Humans
Incidence
Longitudinal Studies
Models, Statistical
Polymorphism, Single Nucleotide
Reproducibility of Results

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 25854837
DOI: 10.1111/biom.12310
PMCID: PMC4601568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.