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Article

Set-based tests for genetic association in longitudinal studies.

Biometrics - 1 Sept 2015

He Zihuai, Zhang Min, Lee Seunggeun, Smith Jennifer A, Guo Xiuqing, Palmas Walter, Kardia Sharon L R, Diez Roux Ana V, Mukherjee Bhramar

Abstract excerpt

Genetic association studies with longitudinal markers of chronic diseases (e.g., blood pressure, body mass index) provide a valuable opportunity to explore how genetic variants affect traits over time by utilizing the full trajectory of longitudinal outcomes. Since these traits are likely influenced by the joint effect of multiple variants in a gene, a joint analysis of these variants considering linkage...

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Identifiers

PMID: 25854837
DOI: 10.1111/biom.12310
PMCID: PMC4601568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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