Article
Genetically determined height and coronary artery disease.
The New England journal of medicine - 23 Apr 2015
Nelson Christopher P, Hamby Stephen E, Saleheen Danish, Hopewell Jenna C, Zeng Lingyao, Assimes Themistocles L, Kanoni Stavroula, Willenborg Christina, Burgess Stephen, Amouyel Phillipe, Anand Sonia, Blankenberg Stefan, Boehm Bernhard O, Clarke Robert J, Collins Rory, Dedoussis George, Farrall Martin, Franks Paul W, Groop Leif, Hall Alistair S, Hamsten Anders, Hengstenberg Christian, Hovingh G Kees, Ingelsson Erik, Kathiresan Sekar, Kee Frank, König Inke R, Kooner Jaspal, Lehtimäki Terho, März Winifred, McPherson Ruth, Metspalu Andres, Nieminen Markku S, O'Donnell Christopher J, Palmer Colin N A, Peters Annette, Perola Markus, Reilly Muredach P, Ripatti Samuli, Roberts Robert, Salomaa Veikko, Shah Svati H, Schreiber Stefan, Siegbahn Agneta, Thorsteinsdottir Unnur, Veronesi Giovani, Wareham Nicholas, Willer Cristen J, Zalloua Pierre A, Erdmann Jeanette, Deloukas Panos, Watkins Hugh, Schunkert Heribert, Danesh John, Thompson John R, Samani Nilesh J
Abstract excerpt
BACKGROUND: The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS: We used a genetic approach to investigate the association between height and CAD, using 180 height-associated genetic variants. We tested the association between a change in genetically determined height of 1 SD (6.5 cm) with the risk of CAD in 65,066...
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