Article
Genetic Predisposition to Central Obesity and Risk of Type 2 Diabetes: Two Independent Cohort Studies.
Diabetes care - 1 Jul 2015
Huang Tao, Qi Qibin, Zheng Yan, Ley Sylvia H, Manson JoAnn E, Hu Frank B, Qi Lu
Abstract excerpt
OBJECTIVE: Abdominal obesity is a major risk factor for type 2 diabetes (T2D). We aimed to examine the association between the genetic predisposition to central obesity, assessed by the waist-to-hip ratio (WHR) genetic score, and T2D risk. RESEARCH DESIGN AND METHODS: The current study included 2,591 participants with T2D and 3,052 participants without T2D of European ancestry from the Nurses' Health Study (NHS)...
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