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Article

Peroxisome proliferator‐activated receptor (PPAR)γ is expressed by human spermatozoa: Its potential role on the sperm physiology

13 Sept 2006

Abstract excerpt

The peroxisome proliferation-activated receptor gamma (PPARgamma) is mainly expressed in the adipose tissue and integrates the control of energy, lipid, and glucose homeostasis. The present study, by means of RT-PCR, Western blot, and immunofluorescence techniques, demonstrates that human sperm express the PPARgamma. The functionality of the receptor was evidenced by 15-deoxy-12,14-prostaglandin J(2) (PGJ2) and...

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PMID: 16972250
DOI: 10.1002/jcp.20807

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