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Article

The Biology of the Peroxisome Proliferator-activated Receptor System in the Female Reproductive Tract

1 Jun 2013

Abstract excerpt

Fuel sensors such as glucose, insulin or leptin, are known to be directly involved in the regulation of fertility at each level of the hypothalamic-pituitary-gonadal axis. The discovery of the peroxisome proliferator-activated receptor (PPAR) family of transcription factors has revealed the link between lipid/glucose availability and long-term metabolic adaptation. By binding to specific regions of DNA in...

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PMID: 23565653
DOI: 10.2174/1381612811319250010

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