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Article

The Role of Peroxisome Proliferator‐Activated Receptors in the Development and Physiology of Gametes and Preimplantation Embryos

1 Jan 2008

Abstract excerpt

In several species, a family of nuclear receptors, the peroxisome proliferator-activated receptors (PPARs) composed of three isotypes, is expressed in somatic cells and germ cells of the ovary as well as the testis. Invalidation of these receptors in mice or stimulation of these receptors in vivo or in vitro showed that each receptor has physiological roles in the gamete maturation or the embryo development. In...

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PMID: 18354728
DOI: 10.1155/2008/732303

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