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Article

Linking microtubules to Parkinson's disease: the case of parkin.

Biochemical Society transactions - 1 Apr 2015

Cappelletti Graziella, Casagrande Francesca, Calogero Alessandra, De Gregorio Carmelita, Pezzoli Gianni, Cartelli Daniele

Abstract excerpt

Microtubules (MTs) are dynamic polymers consisting of α/β tubulin dimers and playing a plethora of roles in eukaryotic cells. Looking at neurons, they are key determinants of neuronal polarity, axonal transport and synaptic plasticity. The concept that MT dysfunction can participate in, and perhaps lead to, Parkinson's disease (PD) progression has been suggested by studies using toxin-based and genetic...

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PMID: 25849932
DOI: 10.1042/BST20150007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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