Article
Genetic association of IL-6, TNF-α and SDF-1 polymorphisms with serum cytokine levels in diabetic foot ulcer.
Gene - 1 Jul 2015
Dhamodharan Umapathy, Viswanathan Vijay, Krishnamoorthy Ezhilarasi, Rajaram Rama, Aravindhan Vivekanandhan
Abstract excerpt
The IL-6 -174G/C (rs1800795), TNF-α -308G/A (rs1800629) and -238G/A (rs361525) and SDF-1 801G/A (rs1801157) are well characterized SNPs which have previously been linked to various diabetic complications. However, the involvement of these SNPs in DFU remains poorly studied. In the present study we looked at the association of these SNPs with DFU (disease phenotype) and correlated it with the serum levels of...
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