Article
Study of linkage between glutathione pathway and the antibiotic resistance of Escherichia coli from patients' swabs.
International journal of molecular sciences - 31 Mar 2015
Kominkova Marketa, Michalek Petr, Cihalova Kristyna, Guran Roman, Cernei Natalia, Nejdl Lukas, Smerkova Kristyna, Dostalova Simona, Chudobova Dagmar, Heger Zbynek, Vesely Radek, Gumulec Jaromir, Kynicky Jindrich, Xhaxhiu Kledi, Zitka Ondrej, Adam Vojtech, Kizek Rene
Abstract excerpt
In this work, we focused on the differences between bacterial cultures of E. coli obtained from swabs of infectious wounds of patients compared to laboratory E. coli. In addition, blocking of the protein responsible for the synthesis of glutathione (γ-glutamylcysteine synthase-GCL) using 10 mM bu...
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