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Placental melatonin system is present throughout pregnancy and regulates villous trophoblast differentiation

1 Apr 2015

Abstract excerpt

Melatonin is highly produced in the placenta where it protects against molecular damage and cellular dysfunction arising from hypoxia/re-oxygenation-induced oxidative stress as observed in primary cultures of syncytiotrophoblast. However, little is known about melatonin and its receptors in the human placenta throughout pregnancy and their role in villous trophoblast development. The purpose of this study was to...

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PMID: 25833399
DOI: 10.1111/jpi.12236

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