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Interaction Between Functional Genetic Variation of DRD2 and Cannabis Use on Risk of Psychosis

31 Mar 2015

Abstract excerpt

Both cannabis use and the dopamine receptor (DRD2) gene have been associated with schizophrenia, psychosis-like experiences, and cognition. However, there are no published data investigating whether genetically determined variation in DRD2 dopaminergic signaling might play a role in individual susceptibility to cannabis-associated psychosis. We genotyped (1) a case-control study of 272 patients with their first...

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PMID: 25829376
DOI: 10.1093/schbul/sbv032

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