Population heterogeneity in Cryptococcus neoformans: Impact on pathogenesis

Abstract excerpt

Cryptococcus neoformans was first isolated from a patient in 1894 [1] and 130 years later, it remains a prevalent global threat, especially for people living with human immunodeficiency virus (HIV) [2]. Human–Cryptococcus interaction begins in childhood, after inhalation of basidiospores which are widespread in the environment. Typically, this interaction advances in one of the 4 major possible ways: (I)...

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