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Article

Temporal phenotypic features distinguish polarized macrophages in vitro.

Autoimmunity - 1 May 2015

Melton David W, McManus Linda M, Gelfond Jonathan A L, Shireman Paula K

Abstract excerpt

Macrophages are important in vascular inflammation and environmental factors influence macrophage plasticity. Macrophage transitions into pro-inflammatory (M1) or anti-inflammatory (M2) states have been defined predominately by measuring cytokines in culture media (CM). However, temporal relationships between cellular and secreted cytokines have not been established. We measured phenotypic markers and cytokines...

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Identifiers

PMID: 25826285
DOI: 10.3109/08916934.2015.1027816
PMCID: PMC4681525

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