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Article

Genetic and immunologic susceptibility to statin-related myopathy.

Atherosclerosis - 1 May 2015

Patel Jaideep, Superko H Robert, Martin Seth S, Blumenthal Roger S, Christopher-Stine Lisa

Abstract excerpt

Statin-related myopathy (SRM) undermines drug adherence that is critical for achieving the benefits of lipid-lowering therapy. While the exact mechanism of SRM remains largely unknown, recent evidence supports specific genetic and immunologic influence on the development of intolerance. Genes of interest include those involved in the pharmacokinetics of statin response (i.e. drug metabolism, uptake transporters,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25818852
DOI: 10.1016/j.atherosclerosis.2015.03.025

Genes

SRM

Provenance

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