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Article

Pharmacogenomics, lipid disorders, and treatment options.

Clinical pharmacology and therapeutics - 1 Jul 2014

Gryn S E, Hegele R A

Abstract excerpt

Statins form the backbone of lipid-lowering therapy in the prevention of cardiovascular disease. Numerous studies have evaluated the effect of genomics on the clinical efficacy and adverse effects of statins. Several gene variants that can be linked to either the pharmacokinetics or pharmacodynamics of statins have been identified as potentially important, although there are some discrepant findings among...

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Source

Identifiers

PMID: 24722394
DOI: 10.1038/clpt.2014.82

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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