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Models of Breast Morphogenesis Based on Localization of Stem Cells in the Developing Mammary Lobule

1 Apr 2015

Abstract excerpt

Characterization of normal breast stem cells is important for understanding their role in breast development and in breast cancer. However, the identity of these cells is a subject of controversy and their localization in the breast epithelium is not known. In this study, we utilized a novel approach to analyze the morphogenesis of mammary lobules, by combining one-dimensional theoretical models and...

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PMID: 25818813
DOI: 10.1016/j.stemcr.2015.02.013

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