Article
Genetic markers of Restless Legs Syndrome in Parkinson disease.
Parkinsonism & related disorders - 1 Jun 2015
Gan-Or Ziv, Alcalay Roy N, Bar-Shira Anat, Leblond Claire S, Postuma Ronald B, Ben-Shachar Shay, Waters Cheryl, Johnson Amelie, Levy Oren, Mirelman Anat, Gana-Weisz Mali, Dupré Nicolas, Montplaisir Jacques, Giladi Nir, Fahn Stanley, Xiong Lan, Dion Patrick A, Orr-Urtreger Avi, Rouleau Guy A
Abstract excerpt
INTRODUCTION: Several studies proposed that Restless Legs Syndrome (RLS) and Parkinson disease (PD) may be clinically and/or etiologically related. To examine this hypothesis, we aimed to determine whether the known RLS genetic markers may be associated with PD risk, as well as with PD subtype. METHODS: Two case-control cohorts from Tel-Aviv and New-York, including 1133 PD patients and 867 controls were genotyped...
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