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Article

Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients.

Pharmacogenetics and genomics - 1 Jun 2015

van Huis-Tanja Lieke H, Ewing Ewoud, van der Straaten R J H M, Swen Jesse J, Baak-Pablo Renée F, Punt C J A, Gelderblom A J, Guchelaar Henk-Jan

Abstract excerpt

BACKGROUND AND AIM: Pharmacogenetic studies continue to search for pretreatment predictors of chemotherapeutic efficacy and toxicity in metastatic colorectal cancer. Both genome-wide association studies and candidate gene studies have yielded potential genetic markers for chemosensitivity. We conducted a clinical association study, validating the effect of specific genetic markers cited in recently published...

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Source

Identifiers

PMID: 25815774
DOI: 10.1097/FPC.0000000000000119

Genes

MTRR
ADCY2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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