Article
Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting.
Genome research - 1 Jan 2015
Tong Steven Y C, Holden Matthew T G, Nickerson Emma K, Cooper Ben S, Köser Claudio U, Cori Anne, Jombart Thibaut, Cauchemez Simon, Fraser Christophe, Wuthiekanun Vanaporn, Thaipadungpanit Janjira, Hongsuwan Maliwan, Day Nicholas P, Limmathurotsakul Direk, Parkhill Julian, Peacock Sharon J
Abstract excerpt
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infection. Whole-genome sequencing of MRSA has been used to define phylogeny and transmission in well-resourced healthcare settings, yet the greatest burden of nosocomial infection occurs in resource-restricted settings where barriers to transmission are lower. Here, we study the flux and genetic diversity of MRSA on ward and...
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