Article
Deregulated expression of Aurora kinases is not a prognostic biomarker in papillary thyroid cancer patients.
PloS one - 1 Jan 2015
Baldini Enke, Tuccilli Chiara, Prinzi Natalie, Sorrenti Salvatore, Falvo Laura, De Vito Corrado, Catania Antonio, Tartaglia Francesco, Mocini Renzo, Coccaro Carmela, Alessandrini Stefania, Barollo Susi, Mian Caterina, Antonelli Alessandro, De Antoni Enrico, D'Armiento Massimino, Ulisse Salvatore
Abstract excerpt
A number of reports indicated that Aurora-A or Aurora-B overexpression represented a negative prognostic factor in several human malignancies. In thyroid cancer tissues a deregulated expression of Aurora kinases has been also demonstrated, but no information regarding its possible prognostic role in differentiated thyroid cancer is available. Here, we evaluated Aurora-A and Aurora-B mRNA expression and its...
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