Article
EW_dmGWAS: edge-weighted dense module search for genome-wide association studies and gene expression profiles.
Bioinformatics (Oxford, England) - 1 Aug 2015
Wang Quan, Yu Hui, Zhao Zhongming, Jia Peilin
Abstract excerpt
We previously developed dmGWAS to search for dense modules in a human protein-protein interaction (PPI) network; it has since become a popular tool for network-assisted analysis of genome-wide association studies (GWAS). dmGWAS weights nodes by using GWAS signals. Here, we introduce an upgraded algorithm, EW_dmGWAS, to boost GWAS signals in a node- and edge-weighted PPI network. In EW_dmGWAS, we utilize...
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