Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis.

doi:10.1200/JCO.2014.57.7080

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Article

Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Apr 2015

Dybkær Karen, Bøgsted Martin, Falgreen Steffen, Bødker Julie S, Kjeldsen Malene K, Schmitz Alexander, Bilgrau Anders E, Xu-Monette Zijun Y, Li Ling, Bergkvist Kim S, Laursen Maria B, Rodrigo-Domingo Maria, Marques Sara C, Rasmussen Sophie B, Nyegaard Mette, Gaihede Michael, Møller Michael B, Samworth Richard J, Shah Rajen D, Johansen Preben, El-Galaly Tarec C, Young Ken H, Johnsen Hans E

Abstract excerpt

PURPOSE: Current diagnostic tests for diffuse large B-cell lymphoma use the updated WHO criteria based on biologic, morphologic, and clinical heterogeneity. We propose a refined classification system based on subset-specific B-cell-associated gene signatures (BAGS) in the normal B-cell hierarchy, hypothesizing that it can provide new biologic insight and diagnostic and prognostic value. PATIENTS AND METHODS: We...

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Identifiers

PMID: 25800755
DOI: 10.1200/JCO.2014.57.7080
PMCID: PMC4397280

Genes

LMO2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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