Article
Vitamin D metabolic pathway genes and pancreatic cancer risk.
PloS one - 1 Jan 2015
Arem Hannah, Yu Kai, Xiong Xiaoqin, Moy Kristin, Freedman Neal D, Mayne Susan T, Albanes Demetrius, Arslan Alan A, Austin Melissa, Bamlet William R, Beane-Freeman Laura, Bracci Paige, Canzian Federico, Cotterchio Michelle, Duell Eric J, Gallinger Steve, Giles Graham G, Goggins Michael, Goodman Phyllis J, Hartge Patricia, Hassan Manal, Helzlsouer Kathy, Henderson Brian, Holly Elizabeth A, Hoover Robert, Jacobs Eric J, Kamineni Aruna, Klein Alison, Klein Eric, Kolonel Laurence N, Li Donghui, Malats Núria, Männistö Satu, McCullough Marjorie L, Olson Sara H, Orlow Irene, Peters Ulrike, Petersen Gloria M, Porta Miquel, Severi Gianluca, Shu Xiao-Ou, Visvanathan Kala, White Emily, Yu Herbert, Zeleniuch-Jacquotte Anne, Zheng Wei, Tobias Geoffrey S, Maeder Dennis, Brotzman Michelle, Risch Harvey, Sampson Joshua N, Stolzenberg-Solomon Rachael Z
Abstract excerpt
Evidence on the association between vitamin D status and pancreatic cancer risk is inconsistent. This inconsistency may be partially attributable to variation in vitamin D regulating genes. We selected 11 vitamin D-related genes (GC, DHCR7, CYP2R1, VDR, CYP27B1, CYP24A1, CYP27A1, RXRA, CRP2, CASR and CUBN) totaling 213 single nucleotide polymorphisms (SNPs), and examined associations with pancreatic...
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