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Article

Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity?

19 Mar 2015

Abstract excerpt

BACKGROUND: We have previously characterized 19 ependymal tumors using Giemsa banding and high-resolution comparative genomic hybridization. The aim of this study was to analyze these tumors searching for fusion genes. METHODS: RNA sequencing was performed in 12 samples. Potential fusion transcripts were assessed by seed count and structural chromosomal aberrations. Transcripts of interest were validated using...

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PMID: 25795305
DOI: 10.1093/neuonc/nov039

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