Article
EGFR Promoter Methylation, EGFR Mutation, and HPV Infection in Chinese Cervical Squamous Cell Carcinoma.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Oct 2015
Zhang Wei, Jiang Yinghao, Yu Qingmiao, Qiang Shaoying, Liang Ping, Gao Yane, Zhao Xingye, Liu Wenchao, Zhang Ju
Abstract excerpt
Therapy strategy toward epidermal growth factor receptor (EGFR) inhibition in cervical cancer has been ongoing. EGFR promoter methylation status and EGFR tyrosine kinase inhibitor-sensitive mutations in cervical cancer may be significant for clinical outcome prediction using anti-EGFR treatment. In this study, EGFR tyrosine kinase inhibitor-sensitive mutations, EGFR exons 18, 19, and 21 mutations, were detected...
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