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Article

Regulation of pattern formation and gene amplification during Drosophila oogenesis by the miR-318 microRNA.

Genetics - 1 May 2015

Ge Wanzhong, Deng Qiannan, Guo Ting, Hong Xin, Kugler Jan-Michael, Yang Xiaohang, Cohen Stephen M

Abstract excerpt

Pattern formation during epithelial development requires the coordination of multiple signaling pathways. Here, we investigate the functions of an ovary-enriched miRNA, miR-318, in epithelial development during Drosophila oogenesis. mir-318 maternal loss-of-function mutants were female-sterile and laid eggs with abnormal morphology. Removal of mir-318 disrupted the dorsal-anterior follicle cell patterning,...

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Identifiers

PMID: 25786856
DOI: 10.1534/genetics.115.174748
PMCID: PMC4423367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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