Article
Association studies of calcium-sensing receptor (CaSR) polymorphisms with serum concentrations of glucose and phosphate, and vascular calcification in renal transplant recipients.
PloS one - 1 Jan 2015
Babinsky Valerie N, Hannan Fadil M, Youhanna Sonia C, Maréchal Céline, Jadoul Michel, Devuyst Olivier, Thakker Rajesh V
Abstract excerpt
BACKGROUND: Cardiovascular disease is the major cause of death in renal transplant recipients (RTRs) and linked to arterial calcification. The calcium-sensing receptor (CaSR), a G-protein coupled receptor, plays a pivotal role in extracellular calcium homeostasis and is expressed in the intimal and medial layers of the arterial wall. We investigated whether common CASR gene variants are predictors for aortic and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.