Article
The clinical significance of parathyroid tissue calcium sensing receptor gene polymorphisms and expression levels in end-stage renal disease patients.
Clinical nephrology - 1 Aug 2009
Eren P A, Turan K, Berber I, Canbakan M, Kara M, Tellioglu G, Bugan U, Sevinç C, Turkmen F, Titiz M I
Abstract excerpt
BACKGROUND: The calcium sending receptor (CaSR) allows parathyroid and kidney tubular cells to regulate PTH secretion and tubular calcium reabsorption. In the present report, we examined the relationship between CaSR gene polymorphisms and parathyroid CaSR expression and serum calcium/parathyroid hormone (PTH) levels and clinical progress in ESRD patients in the Turkish population. METHODS: We genotyped the CaSR...
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