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Article

Sudden death associated with QT interval prolongation and KCNQ1 gene mutation in a family of English Springer Spaniels.

Journal of veterinary internal medicine - 1 Jan 2000

Ware W A, Reina-Doreste Y, Stern J A, Meurs K M

Abstract excerpt

BACKGROUND: A 5-year-old, healthy English Springer Spaniel died suddenly 4 months after delivering a litter of 7 puppies. Within 4 months of the dam's death, 3 offspring also died suddenly. HYPOTHESIS: Abnormal cardiac repolarization, caused by an inherited long QT syndrome, is thought to be responsible for arrhythmias leading to sudden death in this family. ANIMALS: Four remaining dogs from the affected litter...

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Source

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Identifiers

PMID: 25779927
DOI: 10.1111/jvim.12550
PMCID: PMC4895492

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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