Article
Effect of dipyridamole on myocardial reperfusion injury: A double-blind randomized controlled trial in patients undergoing elective coronary artery bypass surgery.
Clinical pharmacology and therapeutics - 1 Apr 2016
El Messaoudi S, Wouters C W, van Swieten H A, Pickkers P, Noyez L, Kievit P C, Abbink E J, Rasing-Hoogveld A, Bouw T P, Peters J G, Coenen M J H, Donders A R T, Riksen N P, Rongen G A
Abstract excerpt
Dipyridamole reduces reperfusion-injury in preclinical trials and may be beneficial in patients undergoing coronary angioplasty, but its effect on patients undergoing coronary artery bypass grafting (CABG) is unknown. We hypothesized that dipyridamole limits myocardial reperfusion-injury in patients undergoing CABG. The trial design was a double-blind trial randomizing between pretreatment with dipyridamole or...
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