Article
Genetic variability of glutathione S-transferases influences treatment outcome of breast cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2015
Zhou Liang, Huang Anzhong, Zhang Dawei, Yao Junliang, Zhang Yong, Li Xuejiao
Abstract excerpt
We investigated the relationship between the clinical outcome and the GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms in breast cancer patients with chemotherapy. A total of 420 consecutive breast cancer patients diagnosed between January 2010 and December 2011 were eligible for inclusion in our retrospective study. The designs of the assay and SNP genotyping of GSTM1 null/present, GSTT1...
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