Article
Serotonergic genes and depressive disorder in acute coronary syndrome: The Korean depression in ACS (K-DEPACS) study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jun 2015
Kim Jae-Min, Stewart Robert, Kang Hee-Ju, Bae Kyung-Yeol, Kim Sung-Wan, Shin Il-Seon, Hong Young Joon, Ahn Youngkeun, Jeong Myung Ho, Park Sung-Woo, Kim Young-Hoon, Yoon Jin-Sang
Abstract excerpt
Genes coding for the serotonergic pathway have been associated with depressive disorders. However, these associations have rarely been tested in acute coronary syndrome (ACS) patients vulnerable to depression. This study aimed to investigate whether polymorphisms of serotonin transporter (5-HTT) and serotonin 2a receptor (5-HTR2a) genes are associated with occurrence of depressive disorder in ACS. 969 patients...
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