Article
Length Polymorphisms in the Angiotensin I-Converting Enzyme Gene and the Serotonin-Transporter-Linked Polymorphic Region Constitute a Risk Haplotype for Depression in Patients with Coronary Artery Disease.
Biochemical genetics - 1 Aug 2020
Meyer Thomas, Rothe Isabel, Staab Julia, Deter Hans-Christian, Fangauf Stella V, Hamacher Stefanie, Hellmich Martin, Jünger Jana, Ladwig Karl-Heinz, Michal Matthias, Petrowski Katja, Ronel Joram, Söllner Wolfgang, Weber Cora, de Zwaan Martina, Williams Redford B, Albus Christian, Herrmann-Lingen Christoph
Abstract excerpt
Genetic variations affecting the course of depressive symptoms in patients with coronary artery disease (CAD) have not yet been well studied. Therefore, we set out to investigate whether distinct haplotypes of the two insertion/deletion polymorphisms in the serotonin-transporter-linked polymorphic region (5-HTTLPR) and the angiotensin I-converting enzyme (ACE) gene located on chromosome 17 can be identified as...
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