Article
Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2015
Jahn Stephan W, Kashofer Karl, Halbwedl Iris, Winter Gerlinde, El-Shabrawi-Caelen Laila, Mentzel Thomas, Hoefler Gerald, Liegl-Atzwanger Bernadette
Abstract excerpt
Desmoplastic malignant melanoma is a distinct melanoma entity histologically subtyped into mixed and pure forms due to significantly reduced lymph node metastases in the pure form. Recent reports investigating common actionable driver mutations have demonstrated a lack of BRAF, NRAS, and KIT mutation in pure desmoplastic melanoma. In search for alternative driver mutations next generation amplicon sequencing for...
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