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Mixed versus pure variants of desmoplastic melanoma: a genetic and immunohistochemical appraisal.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2012

Miller Daniel D, Emley Andrew, Yang Shi, Richards Joanna E, Lee Jung Eun, Deng April, Hoang Mai P, Mahalingam Meera

Abstract excerpt

Desmoplastic melanoma is subclassified into pure and mixed variants with a higher rate of lymph node metastasis in the latter. Given that reasons for these biological differences are not currently known, we investigated these subtypes with techniques that included genetic and immunohistochemical analyses of 43 cases of desmoplastic melanoma (24 pure, 19 mixed). Direct DNA sequencing was performed on BRAFV600E,...

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PMID: 22157936
DOI: 10.1038/modpathol.2011.196

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KIT
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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