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Article

Genotyping and immunohistochemistry of gastrointestinal stromal tumors: An update.

Seminars in diagnostic pathology - 1 Sept 2015

Rubin Brian P, Heinrich Michael C

Abstract excerpt

Gastrointestinal stromal tumors (GISTs) were originally thought to harbor either KIT or platelet-derived growth factor receptor A (PDGFRA) mutations only. However, more recent discoveries have highlighted additional, less common oncogenic driver mutations including NF1, BRAF, and succinate dehydrogenase (SDH) mutations. Genotyping GISTs has become more important since not all genotypes respond equally to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25766843
DOI: 10.1053/j.semdp.2015.02.017

Genes

PDGFRA
SDHA
KIT
BRAF
SDHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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