Article
A polymorphism at the translation start site of the vitamin D receptor gene is associated with the response to anti-osteoporotic therapy in postmenopausal women from southern Italy.
International journal of molecular sciences - 10 Mar 2015
Conti Valeria, Russomanno Giusy, Corbi Graziamaria, Toro Giuseppe, Simeon Vittorio, Filippelli Walter, Ferrara Nicola, Grimaldi Michela, D'Argenio Valeria, Maffulli Nicola, Filippelli Amelia
Abstract excerpt
The present study investigated the effect of two single nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, rs1544410 A/G and rs2228570 C/T, in modulating bone mineral density (BMD) and the response to treatment with bisphosphonates or strontium ranelate in postmenopausal osteoporosis (PMO). Four hundred eighteen postmenopausal women from Southern Italy treated with bisphosphonates or strontium...
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