Article
Interrelation between genotypes of the vitamin D receptor gene and serum sex hormone concentrations in the Polish elderly population: the PolSenior study.
Experimental gerontology - 1 Sept 2014
Laczmanski Lukasz, Milewicz Andrzej, Puzianowska-Kuznicka Monika, Lwow Felicja, Kolackov Katarzyna, Mieszczanowicz Urszula, Pawlak Maurycy, Krzyzanowska-Swiniarska Barbara, Bar-Andziak Ewa, Chudek Jerzy, Mossakowska Malgorzata
Abstract excerpt
AIM: Vitamin D co-regulates the synthesis of sex hormones. Therefore, the aim of this study was to determine whether the presence of certain genotypes of the vitamin D receptor gene (VDR) is associated with the serum levels of sex hormones in the elderly Polish population. MATERIALS AND METHODS: The rs10735810, rs1544410, rs7975232, and rs731236 polymorphisms of VDR, the serum levels of testosterone and...
Read the complete abstract on PubMed