Article
Therapy of corneal endothelial dysfunction with corneal endothelial cell-like cells derived from skin-derived precursors.
Scientific reports - 17 Oct 2017
Shen Lin, Sun Peng, Zhang Canwei, Yang Le, Du Liqun, Wu Xinyi
Abstract excerpt
Corneal endothelial dysfunction occurs when corneal endothelial cells (CECs) are dramatically lost and eventually results in vision loss. Corneal transplantation is the only solution at present. However, corneal transplantation requires a fresh human cornea and there is a worldwide shortage of donors. Therefore, finding new functional CECs to replace human CECs is urgent. Skin-derived precursors (SKPs) can be...
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