Article
Understanding genetic variation and function- the applications of next generation sequencing.
Seminars in cell & developmental biology - 1 Apr 2012
Harrison Richard J
Abstract excerpt
Next generation sequencing (NGS) technology has had a transformatory effect upon population-level studies linking genetic variation to gene function. In this review, I briefly describe recent studies that have used top-down genome scanning and population genetic approaches to identify loci under recent selection, as well as some examples of how large NGS datasets can be deployed to detect the total level of...
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