Article
Potential and real 'antineoplastic' and metabolic effect of metformin in diabetic and nondiabetic postmenopausal females.
Future oncology (London, England) - 1 Jan 2015
Berstein Lev M, Vasilyev Dmitry A, Iyevleva Aglaya G, Boyarkina Marina P, Poroshina Tatyana E, Khadzhimba Angela S, Imyanitov Evgeny N
Abstract excerpt
AIM: The goal of this study was to determine if the single nucleotide polymorphisms marking potential sensitivity to metformin (MF) correlate with hormone-metabolic status as well as with actual response to MF in postmenopausal cancer patients with or without Type 2 diabetes mellitus and in diabetics without cancer. PATIENTS & METHODS: The carriage of ten different SNPs was evaluated in all patients by PCR, and...
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