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Paternal Age Matters: Association with Sperm Criteria’s- Spermatozoa DNA Integrity and Methylation Profile

27 Jul 2023

Abstract excerpt

Advanced age has been reported to negatively affect sperm parameters and spermatozoa DNA integrity. A decline in sperm criteria was also associated with altered epigenetic marks such as DNA methylation with a potential downstream impact on in vitro fertilization success and clinical outcomes. The aim of the present retrospective study was to clarify the association between advanced paternal age (APA) and sperm...

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PMID: 37568329
DOI: 10.3390/jcm12154928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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