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Alleles of newly identified barley gene HvPARP3 exhibit changes in efficiency of DNA repair.

DNA repair - 1 Apr 2015

Stolarek Magdalena, Gruszka Damian, Braszewska-Zalewska Agnieszka, Maluszynski Miroslaw

Abstract excerpt

Genome integrity is constantly challenged by endo- and exogenous DNA-damaging factors. The influence of genotoxic agents causes an accumulation of DNA lesions, which if not repaired, become mutations that can cause various abnormalities in a cell metabolism. The main pathway of DSB repair, which is based on non-homologous recombination, is canonical non-homologous end joining (C-NHEJ). It has been shown that this...

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Identifiers

PMID: 25753810
DOI: 10.1016/j.dnarep.2015.02.018

Genes

PARP3

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