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Association of Enterovirus 71 encephalitis with the interleukin-8 gene region in Chinese children.

Infectious diseases (London, England) - 1 Jun 2015

Li Jian, Lin Aiwei, Yu Chengwen, Zhang Zhaofang, Xu Daoyan, Hu Wei, Liu Liyan, Wang Shaoning, Nie Xiuzhen, Sun Wenhui, Gai Zhongtao, Chen Zongbo

Abstract excerpt

The study was performed in 36 Chinese patients with Enterovirus 71 (EV71) encephalitis and 141 patients with EV71-related hand, foot and mouth disease (HFMD) without encephalitis. Genotyping was determined by polymerase chain reaction- restriction fragment length polymorphism. Patients with EV71 encephalitis had a significantly higher frequency of interleukin-8 (IL-8)-251TT genotype than patients with...

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Identifiers

PMID: 25751776
DOI: 10.3109/00365548.2015.1007473

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